Available inference methods

Methods available individually

Fixed Protein Methods

Name	Source	Astex Benchmarked	PoseBusters Benchmarked	DockGen Benchmarked	CASP Benchmarked
DiffDock	Corso et al.	✓	✓	✓	✓
FABind	Pei et al.	✓	✓	✓	✗
AutoDock Vina	Eberhardt et al.	✓	✓	✓	✓
TULIP		✓	✓	✗	✓

Flexible Protein Methods

Name	Source	Astex Benchmarked	PoseBusters Benchmarked	DockGen Benchmarked	CASP Benchmarked
DynamicBind	Lu et al.	✓	✓	✓	✓
NeuralPLexer	Qiao et al.	✓	✓	✓	✓
FlowDock	Morehead et al.	✓	✓	✓	✓
RoseTTAFold-All-Atom	Krishna et al.	✓	✓	✓	✓
Chai-1	Chai Discovery	✓	✓	✓	✓
Boltz	Wohlwend et al.	✓	✓	✓	✓
AlphaFold 3	Abramson et al.	✓	✓	✓	✓

Methods available for ensembling

Fixed Protein Methods

Name	Source	Astex Benchmarked	PoseBusters Benchmarked	DockGen Benchmarked	CASP Benchmarked
DiffDock	Corso et al.	✓	✓	✓	✓
AutoDock Vina	Eberhardt et al.	✓	✓	✓	✓
TULIP		✓	✓	✗	✓

Flexible Protein Methods

Name	Source	Astex Benchmarked	PoseBusters Benchmarked	DockGen Benchmarked	CASP Benchmarked
DynamicBind	Lu et al.	✓	✓	✓	✓
NeuralPLexer	Qiao et al.	✓	✓	✓	✓
FlowDock	Morehead et al.	✓	✓	✓	✓
RoseTTAFold-All-Atom	Krishna et al.	✓	✓	✓	✓
Chai-1	Chai Discovery	✓	✓	✓	✓
Boltz	Wohlwend et al.	✓	✓	✓	✓
AlphaFold 3	Abramson et al.	✓	✓	✓	✓

Note

Have a new method to add? Please let us know by creating a pull request. We would be happy to work with you to integrate new methodology into this benchmark!